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Image Search Results
Journal: Stem cell research & therapy
Article Title: Extracellular matrix derived from Wharton's Jelly-derived mesenchymal stem cells promotes angiogenesis via integrin αVβ3/c-Myc/P300/VEGF.
doi: 10.1186/s13287-022-03009-5
Figure Lengend Snippet: Fig. 5 Integrin αVβ3 mediated the effect of WJ-MSCs ECM on HUVECs. a–e mRNA expressions of integrin α5, αV, β1, β3, and β5 in HUVECs were determined by RT-qPCR. Mean ± S.E.M., n = 5. f, o–s Protein expressions of FAK, p-FAK, P38, p-P38 and VEGF in HUVECs were determined by western blotting. Mean ± S.E.M. n = 3. g–n Matrigel tube formation assay images of cumulative tube length. Bar = 50 μm. HY-100563: integrin αVβ3 specific antagonist. HY-13535A: integrin α5β1 specific antagonist. The P value was calculated using one-way ANOVA and independent samples t-test. *P < 0.05, **P < 0.01 versus control
Article Snippet: FAK inhibitors (PF573228), antagonist for integrin αVβ3 (HY-100563) and
Techniques: Quantitative RT-PCR, Western Blot, Tube Formation Assay, Control